Jannik Sinner has pulled out of the US Open. The world No. 1 announced on Instagram that a right knee injury he picked up at Wimbledon has not healed in time for the year's final Grand Slam, ending days of speculation over his fitness.

"Even though I have been working hard with my team and my medical staff, we have now had to make the difficult decision that I will not be able to compete at the US Open this year," Sinner wrote. "I am of course very sad and disappointed, because New York has a special place in my heart."

The 25-year-old Italian has not played a match since successfully defending his Wimbledon title last month, beating Alexander Zverev in the final. The same knee problem, managed with his medical team in Milan, had already forced him out of the National Bank Open in Canada and the Cincinnati Masters, the two big hard-court tune-up events ahead of Flushing Meadows.

It is the first Grand Slam Sinner has missed since he made his major debut at the 2019 US Open, a run stretching back through his rise to No. 1. He won the title in New York in 2024 and returned to the final last year, where he lost to Carlos Alcaraz.

According to the ATP and US Open organizers, Sinner is the twelfth player to withdraw from the 2026 US Open singles fields since the initial entry lists were released, underlining how heavily the packed post-Wimbledon hard-court swing has taken its toll this season.

His absence reshapes the men's draw at Flushing Meadows, where Alcaraz arrives as the defending champion after beating Sinner in last year's final and will now be the clear favorite without his fiercest rival in the field.

There is no confirmed timeline yet for Sinner's return. His team has indicated the focus for now is on rehabilitation, with the Asian hard-court swing in the autumn seen as a more realistic target for a comeback.